You are invited to the upcoming seminar on "Astroglial Cuts Through the Alzheimer’s Manifold".
Presenter:
Dr Maurizio De Pitta
Assistant Professor
Neurophysiology Department of Physiology,
Temerty Faculty of Medicine
University of Toronto, Canada
Title: Astroglial Cuts Through the Alzheimer’s Manifold
Abstract:
The multifactorial etiology of Alzheimer's disorder presents formidable challenges in both diagnosis and treatment. These challenges can be effectively conceptualized through a mathematical framework akin to a manifold, representing the intricate landscape of the pathology. Within this framework, the dimensions and contours of this manifold must be carefully elucidated to establish reliable approaches to Alzheimer's theranostics. In this context, our focus is on navigating the Alzheimer's manifold with a specific emphasis on the astroglial component of the disease. Emerging evidence highlights the potential of astroglia molecular biology and genetic signatures as promising avenues for the discovery of novel biomarkers, particularly during the prodromal phase of the disorder. However, the intricate interplay between astroglia markers and the risk of developing dementia phenotypes remains a subject of ongoing investigation, warranting further exploration.
Seminar Details:
Date: 24 November 2023, Friday
Time: 12:00pm to 1:00pm
Venue:
Meeting Room 7C, Duke-NUS
Host:
Assoc Prof Adam Claridge-Chang
Principal Investigator
Neuroscience & Behavioural Disorders Programme
Duke-NUS
All are welcome. No registration is required.
