When given a prescription with an increase in the amount of medication to consume, one may naturally be concerned and feel uneasy about the state of their health condition. Conversely, recent research shows that it is important to have medical therapies at the recommended guidelines for heart failure, whereby an uptitration of drugs dosage can result in better outcome for patients.In a first-ever, multinational real-world data examination of prescription patterns and doses attained for guideline-directed medical therapies in Asian patients suffering from heart failure with HFrEF (refer to visual below), a team of researchers found that the guideline-directed medical therapies at recommended doses are under-utilised in these patients enrolled from across 11 Asian regions in the Asian Sudden Cardiac Death in Heart Failure (ASIAN-HF) registry. These findings were first published in The Lancet Global Health journal on September 2018. The research team, of which eight investigators are from Singapore, analysed prospective data of 5,276 HFrEF patients enrolled in the ASIAN-HF registry since 2012 (where 1066 participants are from Singapore), and studied the prescription patterns and doses attained of guideline-directed medical therapies in Asian HFrEF patients, and the associations with patient outcomes. The research team made the following two observations:
(Click on the above image to expand.)
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