Bicalutamide

Casodex®


Uses


What is Bicalutamide for?

Bicalutamide is a medicine that is used to treat prostate cancer. It works by blocking the effect of a male sex hormone - testosterone.

How should I take or use Bicalutamide?

It is a tablet, to be taken by mouth at the same time every day. It can be taken with food or on an empty stomach, with a glass of water or juice.

What should I do if I forget to take or use Bicalutamide?

If you miss a dose of Bicalutamide, take it as soon as you can if it is within 12 hours of the missed dose. If more than 12 hours have passed, skip the missed dose and go back to your usual dosing time. Do not double dose.


Precaution


What precautions should I take when taking or using Bicalutamide?

  • Inform your doctor or pharmacist of any other medical conditions you have as well as any other medicines or supplements you are taking e.g. warfarin.
  • Use effective birth control methods during treatment with Bicalutamide and for 130 days after stopping treatment.

Side Effects


What are some common side effects of Bicalutamide?

  • Nausea and vomiting may occur and should subside as treatment continues.
  • If nausea occurs, eat and drink in smaller portions, but more frequently.
  • Hot flushes can sometimes occur when you first start taking Bicalutamide.
  • If this occurs, take the tablet at bedtime. If night sweat interferes with sleep, try taking the tablet in the morning.
  • Decreased sexual ability or desire may occur. This will return to normal when the treatment is stopped.
  • Some tiredness and weakness
  • Mild swelling in your ankles, legs or feet
  • Constipation or diarrhea may occur.
  • Exercise if you can, and drink sufficient amount of fluids.

Inform your doctor if any of the following occurs:

  • Skin rashes, hives or itching
  • Shortness of breath or difficulty in breathing
  • Confusion or dizziness
  • Yellowing of the skin or eyes or dark tea-coloured urine

Handling


How should I store Bicalutamide?

  • Keep away from children
  • Keep in a cool, dry place, away from direct sunlight
  • Store at room temperature

For more information


What should I do if I overdose?

If you overdose on this medicine, inform your doctor immediately.

Disclaimers

Please take note that the above is not a complete list of all possible side effects. If you have any concerns about your medication or if you have other side effects that you think are caused by this medication, please consult your doctor or pharmacist.

If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.

This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System, and SingHealth), community pharmacies (Guardian, Unity, and Watsons), and the Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.

Last Updated on March 2018



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