Bortezomib

Velcade®


Uses


What is Bortezomib for?

Bortezomib is a chemotherapy that is used alone or in combination with other agents for the treatment of certain types of cancer.


Precaution


What food or medication should I avoid when I take or use Bortezomib?

  • Grapefruit juice, St John’s Wort, green tea or green tea extracts
  • Ascorbic acid (Vitamin C) supplements, especially 12 hours before and after bortezomib treatment

Side Effects


What are some common side effects of Bortezomib?

Early side effects

  • Nausea and vomiting may occur
    There are medications available, which may prevent or decrease these side effects. If you are given these medications, take them as directed.
Delayed side effects
  • A drop in the blood cell counts may occur 7 to 14 days after treatment
  • Low blood pressure or dizziness
  • Diarrhea or constipation
  • Itch or rash
  • Muscle or joint pain, weakness
  • Tiredness
  • Mild swelling in the limbs
  • Numbness, tingling or burning sensation in the fingers and toes

Inform your doctor if any of the following occurs:

  • Fever of 38°C or higher
  • Excessive diarhea lasting longer than 24 hours
  • Unusual bleeding, bruising or black tarry stools
  • Confusion, loss of balance, vision disturbances, reduced strength or weakness in an arm/leg
  • Shortness of breath or chest pain

Disclaimers

Please take note that the above is not a complete list of all possible side effects. If you have any concerns about your medication or if you have other side effects that you think are caused by this medication, please consult your doctor or pharmacist.

If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.

This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System, and SingHealth), community pharmacies (Guardian, Unity, and Watsons), and the Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.

Last Updated on May 2019



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