Thalidomide

Uses

Precaution

Side Effects

Handling

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Uses

What is Thalidomide for?

Thalidomide is a medication that can be used in the treatment of certain cancers, immune-related conditions and some skin conditions.

How should I take or use Thalidomide?

It is a capsule taken by mouth and swallowed whole with water. Take it once daily, at least one hour after a meal and preferably at bedtime.

What should I do if I forget to take or use Thalidomide?

If you miss a dose, take it as soon as you can if it is within 12 hours of your missed dose. However if more than 12 hours have passed, skip the missed dose and resume your usual dosing schedule. Do not double dose.

Precaution

What precautions should I take when taking or using Thalidomide?

Do not donate blood during treatment and for at least 1 month after stopping Thalidomide.
Effective birth control measures should be taken by both men and women as Thalidomide can cause severe birth defects.
For men: Do not donate sperm during and for 1 month after stopping treatment.

Side Effects

What are some common side effects of Thalidomide?

Drowsiness or lack of energy
Be careful when performing tasks that require alertness. Avoid alcohol.
Headache
Tingling or numbness of the hands and feet
Constipation
Swelling of hands or feet due to fluid retention
Dizziness when changing position
Rise slowly from a seated or lying position.
Decreased white blood cell count

Inform your doctor if any of the following occurs:

Severe skin rash or itch
Fever of 38°C or higher, sore throat
Unusual bleeding, bruising or black sticky stools
Slow or irregular heartbeat
Sudden onset of cough, shortness of breath or chest pain
Severe or unusual swelling of hands or feet
Side effects that are severe

Handling

How should I store Thalidomide?

Keep away from children
Keep in a cool, dry place, away from direct sunlight
Store at room temperature

How should I handle Thalidomide safely?

Do not open, chew or crush the capsules.

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What should I do if I overdose?

If you overdose on this medication, inform your doctor immediately.

Disclaimers

Please take note that the above is not a complete list of all possible side effects. If you have any concerns about your medication or if you have other side effects that you think are caused by this medication, please consult your doctor or pharmacist.

If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.

This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System, and SingHealth), community pharmacies (Guardian, Unity, and Watsons), and the Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.