About the Laboratory
The SKH Musculoskeletal Regenerative Laboratory is a research laboratory at Sengkang General Hospital dedicated to advancing research in muscle health, sarcopenia and healthy ageing.
The laboratory studies how muscles age and regenerate, with the goal of improving prevention, diagnosis and treatment strategies for age-related muscle decline.
By integrating laboratory science, clinical data and translational research, the team aims to transform scientific discoveries into practical solutions that improve patient outcomes and quality of life.
Research Focus Areas
Researchers investigate:
Age-related muscle loss and sarcopenia |
Muscle regeneration and repair |
Inflammation and muscle ageing |
Mitochondrial dysfunction |
Stem cell biology |
Biomakers for early detection of sarcopenia |
Regenerative medicine approaches |
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The laboratory uses:
- Human muscle tissue
- Skeletal muscle organoids
- Cell and stem cell models
- Multi-omics and computational analysis
- Clinical cohort studies
Research Impact
The laboratory aims to:
- Improve early detection of sarcopenia
- Develop better approaches to muscle health assesment
- Support recovery after surgery and illness
- Identify new therapeutic targets
- Advance healthy ageing research
- Translate scientific discoveries into patient care
PEERS Programme for Enhanced Elderly Recovery at SKH which focused on improving recovery outcomes in older adults |
CRC Studying surgical and long-term outcomes in colorectal cancer patients and their impact on quality of life |
SARCO Investigating regulatory mechanisms in muscle stem cells linked to sarcopenia in surgical patients |
DICO Evaluation clinical outcomes and quality of life in patients with diverticular disease and colitis |
D-ECISIVE A clinical trial studying vitamin D maintenance strategies in post-operative patients |
HEROS Studying whether oral nutritional supplementation can improve muscle quality in surgical patients with sarcopenia |
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