Clin Assoc Prof James Li Weiquan

Dr James Li is a Senior Consultant and the Deputy Chairman, Division of Medicine & Inpatient Care at Sengkang General Hospital (SKH). He graduated from the National University of Singapore Yong Loo Lin School of Medicine before going on to obtain his Membership with the Royal Colleges of Physicians (MRCP) in the United Kingdom and Master of Medicine (Internal Medicine) in Singapore. Following that, Dr Li trained as a Fellow in the field of advanced endoscopic imaging and resection in the Osaka International Cancer Institute as part of his Health Manpower Development Programme Award from the Ministry of Health. 

Dr Li specialises in advanced endoscopic imaging and resection techniques for the diagnosis, characterisation and endoscopic resection of early gastrointestinal cancers and premalignant conditions. He is the Director of Quality Improvement for the SingHealth Medicine Academic Clinical Programme.

• MCI
• MRCP (UK)
• MMed (Internal Medicine) (Singapore)
• MBBS (Singapore)

• Deputy Chairman, Division of Medicine & Inpatient Care, SKH, 2025 - Present
• Director of Quality Improvement, Medicine Academic Clinical Programme, SingHealth, 2024 – Present
• Honorary Secretary, Chapter of Gastroenterologists, Academy of Medicine Singapore, 2025 - Present·        
• Director, Endoscopy Centre, Changi General Hospital, 2024 - 2025·    
• Chairman, Artificial Intelligence in Gastrointestinal Endoscopy Singapore (AIGES) Study Group, 2022 – Present·        
• Board Member, Chapter of Gastroenterologists, Academy of Medicine Singapore, 2021 – 2025
• Chairman, Clinical Quality and Quality Improvement, Changi General Hospital, 2018 – 2025·       
•  Member, Young Chapter of Physicians, Academy of Medicine Singapore, 2022 - 2024
• Chairman, Junior Doctor Well-Being Committee, Changi General Hospital, 2021 - 2023
• Associate Programme Director, Gastroenterology, SingHealth, 2019 – 2022
• Member, National Quality Council, Ministry of Health, 2018 - 2021

• Senior Lecturer, National University of Singapore, Yong Loo Lin School of Medicine
• Adjunct Lecturer, Nanyang Technological University Lee Kong Chian School of Medicine

• Faculty Appreciation Award, Residency in SingHealth Excels (RiSE), 2023·        Silver Award, CGH Quality Improvement Festival, 2022
• Best Quality Improvement Project Award, SingHealth Medicine Academic Clinical Programme, 2022
• 2nd Runner up, NUS Medical Education Grand Innovation Challenge (MEGIC), 2021
• Quality Improvement Mentor of the Year, SingHealth Medicine Academic Clinical Programme, 2020
• Outstanding Faculty Award, Residency in SingHealth Excels (RiSE), 2020
• Silver Award, Singapore Health Quality Service Awards, 2020
• Distinguished Young Leader Award, SingHealth Excellence Awards, 2018
• Outstanding Young Educator Award, AMEI (Academic Medicine Education Institute) Golden Apple Awards, 2017
• Outstanding Resident Award, Residency in SingHealth Excels (RiSE), 2017
• Inspiring Resident Educator Award, Residency in SingHealth Excels (RiSE), 2017
• Chief Resident Award, SingHealth Best Junior Doctors, 2016
• Inspiring Resident Educator Award, Residency in SingHealth Excels (RiSE), 2015
• Outstanding Resident Award, Residency in SingHealth Excels (RiSE), 2014
• Outstanding Resident Award, Residency in SingHealth Excels (RiSE), 2013
• "One Life Saved" Resuscitation Distinction Award, Singapore Armed Forces, 2010
• Dean's List, Second Professional (Part 2) Examination, NUS Yong Loo Lin School of Medicine, 2006

1.  Li JW. Where Technology Meets Technique: Computer-Aided Detection and Mucosal Exposure Device to Improve Adenoma Detection. Clinical Endoscopy. 2025. May 23. Online ahead of print
2. Koh FH, Li JW, Wong SH, Lee J, John S, Chong VH, Wu KC, Lui R, Ng SSM, Lam TYT, Lau LHS, Makharia GK, Abdullah M, Maulahela H, Kobayashi N, Sekiguchi M, Byeon JS, Kim HS, Lee YY, Chiu HM, Sung JJY. Asia-Pacific Consensus on the Use of Artificial Intelligence in Colorectal Cancer Screening and Surveillance. iGIE. 2025 Apr 16. In Press, Journal Pre-proof 
3. Ang TL, Hang DV, Li JW, Ho JCL, Sy-Janairo ML, Ali RAR, Makharia GK, Sundaram S, Chantarojanasiri T, Kim HG, Isayama H, Pausawasdi N, Wu K, Syam AF, Aye TT, Rehman S, Niriella MA, Jurawan R, Wang L, Leung WK, Liou JM, Rizan C, Wu JCY, Ooi CJ. APAGE Position Statements on Green and Sustainability in Gastroenterology, Hepatology and Gastrointestinal Endoscopy.Journal of Gastroenterology and Hepatology. 2025 Jan 31. Online ahead of print 
4. Santosa A, Li JW, Tan TC. Digital Health for Equitable Rheumatic Care: Integrating Real-World Experiences to Guide Policy Pathways.Healthcare. 2025; 13(4):438 
5. Santosa A, Li JW, Tan TC.Randomized Controlled Trials of Digital Health Interven tions for Rheumatic Disease Management: A Systematic Review.Bulletin of the World Health Organization. 2025; 103(2):136-147
6. Lai WY, Lin KW, Loi PL, Li JW, Lau LHS, Chiu PWY.Artificial Intelligence in Colonoscopy – Where are we now in 2024? Digestion. 2025 Feb 13:1-28. Online ahead of print. 
7. Rizkala T, Hassan C, Mori Y, Spadaccini M, Antonelli G, Dekker E, Houwen BBSL, Pech O, Baumer S, Rondonotti E, Radaelli F, Li JW, con Renteln D, Misawa M, Facciorusso A, Maselli R, Carrara S, Fugazza A, Capogreco A, Khalaf K, Patel H, Sharma P, Rex D, Repici A.Accuracy of Computer-Aided Diagnosis in Colonoscopy Varies According to Polyp Location: A Systematic Review and Meta-Analysis. Clinical Gastroenterology and Hepatology. 2025; 23(4):531-541 
8. Kawakami Y, Shichijo S, Uedo N, Li JW, Nobre R, Tani Y, Kitagawa D, Ninomiya T, Ueda T, Asada Y, Okubo Y, Kizawa A, Yoshii S, Kanesaka T, Higashino K, Michida T, Ishihara R, Shinno N, Hara H, Omori T, Tanaka Y. Endoscopic Mucosal Resection and Open-lid Submucosal Biopsy for the Diagnosis of Diffuse Infiltrative Gastric Cancer: A Retrospective Observational Study.Scandinavian Journal of Gastroenterology. 2024; 27:1-5 
9. Uedo N, Li JW (2024). Early Gastric Cancer (0-IIc, Differentiated Type) (1). In: Sano Y, Chiu P, Singh R, Uedo N, Goda K, Katada C (eds).Atlas of Advanced Endoscopy. Springer, Singapore.
10. Li JW, Wang LM, Ichimasa K, Lin KW, Ngu JC, Ang TL.Use of Artificial Intelligence in the Management of T1 Colorectal Cancer: A New Tool in the Arsenal of is Deep Learning out of its Depth? Clinical Endoscopy. 2024; 57(1):24-35 
11. Hassan C, Rizkala T, Mori Y, Spadaccini M, Misawa M, Antonelli G, Rondonotti E, Dekker E, Houwen BBSL, Pech O, Baumer S, Li JW, von Renteln D, Haumesser C, Maselli R, Facciorusso A, Loredana C, Menini M, Schiliro A, Khalaf K, Pratel H, Radadiya DK, Bhandari P, Kudo SE, Sultan S, Vandvik PO, Sharma P, Rex DK, Foroutan F, Repici A for the CADx analysis group.Computer-Aided Diagnosis for the Resect-and-Discard Strategy for Colorectal Polyps: A Systematic Review and Meta-Analysis. Lancet Gastroenterology and Hepatology. 2024; 9(11):1010-1019 
12. Kumar R, Ng LXL, Wong YJ, TanCK, Wang LZ, Qiu TY, Wong B, Lin KW, Li JW, Kwek ABE, Ang TL, Gokhle RS, Sivanath TP.Rotational Thromboelastometry Reduces the Need for Preemptive Transfusion in Cirrhosis: A Randomized Controlled Trial. Journal of Clinical and Experimental Hepatology. 2024; 15(1):102409 
13. Hassan C, Misawa M, Rizkala T, Mori Y, Sultan S, Facciorusso A, Antonelli G, Spadaccini M, Houwen BBSL, Rondonotti E, Patel H, Khalaf K, Li JW, Fernandez GM, Bhandari P, Dekker E, Gross S, Berzin T, Vandvik PO, Correale L, Kudo SE, Sharma P, Rex DK, Repici A, Foroutan F; CADx Analysis Study Group.Computer-Aided Diagnosis for Leaving Colorectal Polyps In Situ: A Systematic Review and Meta-analysis. Annals of Internal Medicine. 2024; 177(7):919-928 
14. Zhou Y, Li JW, Uedo N. Multimodal Management of Foregut Neuroendocrine Neoplasms.Best Practice and Research: Clinical Gastroenterology. 2024; 68:101889 
15. Tani Y, Li JW, Uedo N. Texture and Color Enhancement Imaging is Useful for Detection of Small Gastric Adenocarcinoma of Fundic-Gland Type. Journal of Gastroenterology and Hepatology. 2024; 39(5):783-784 
16. Nobre R, Uedo N, Ishihara R, Okuobo Y, Li JW, Maluf-Filho F. Endoscopic Evaluation of the Oral Cavity and Pharynx: How to do it. Endoscopy. 2024; 56:E914-E915 
17. Ueda T, Li JW, Ho SH, Singh R, Uedo N.Precision Endoscopy in the Era of Climate Change and Sustainability.Journal of Gastroenterology and Hepatology. 2024; 39(1):18-27 
18. Ueda T, Ishihara R, Yoshii S, Li JW, Asada Y, Kitagawa D, Kizawa A, Ninomiya T, Okubo Y, Kawakami Y, Tani Y, Shichijo S, Kanesaka T, Yamamoto S, Takeuchi Y, Higashino K, Uedo N, Michida T. Predictors of Technical Difficulty for Trainees in Esophageal Endoscopic Submucosal Dissection.Esophagus. 2024; 21(1):58-66  
19. Nobre R, Uedo N, Ishihara R, Okubo Y, Li JW, Maluf-Filho F. Endoscopic Evaluation of the Oral Cavity and Pharynx: How to do it. Endoscopy. 2024;56(S 01):E914-E915 
20. Li JW, Wu CCH, Lee JWJ, Liang R, Soon GST, Wang LM, Koh XH, Koh CJ, Chew WD, Lin KW, Thian MY, Matthew R, Kim G, Khor CJL, Fock KM, Ang TL, So JBY; Artificial Intelligence in Gastrointestinal Endoscopy Singapore (AIGES) Study Group. Real-world Validation of a Computer-aided Diagnosis System for Prediction of Polyp Histology in Colonoscopy: A Prospective Multicenter Study. American Journal of Gastroenterology. 2023; 118(8):1353-1364 
21. Li JW, Ngu JC, Lim KR, Tay SW, Jiang B, Wijaya R, Yusof S, Ong CJ, Kwek ABE, Ang TL.Colonic Stenting in Acute Malignant Large Bowel Obstruction – an Audit of Efficacy and Safety in a Tertiary Referral Centre in Singapore.Singapore Medical Journal. 2023; 64(10):603-608 
22. Li JW, Uedo N, Shichijo S.Adaptation of Endoscopic Submucosal Dissection Techniques for Endoscopic Full Thickness Resection: A Review of Key Steps and Technical Aspects.VideoGIE. 2023; 9(2):102-106 
23. Li JW, Ang TL.Underwater Endoscopic Submucosal Dissection for Colorectal Tumors: The Next Step in the “Underwater Evolution”? Journal of Gastroenterology and Hepatology. 2023; 38(9):1453-1454 
24. Asada Y, Shichijo S, Li JW, Uedo N.Reopenable-clip Over-the-line Method for Closure of Large Perforation During Esophageal Endoscopic Submucosal Dissection.Endoscopy. 2023; 55:E1103-E1104 
25. Kitagawa D, Shichijo S, Li JW, Okubo Y, Takeuchi Y, Uedo N.Use of a Novel Re-openable Endoclip for the Closure of a Large Mucosal Defect after Endoscopic Submucosal Dissection. Endoscopy 2023; 55(S 01):E883-E884
26. Shichijo S, Tani Y, Li JW, Takeuchi Y, Uedo N.Resection of Large Terminal Ileum Polyp: Usefulness of Underwater Endoscopic Mucosal Resection. VideoGIE. 2023; 8(11):472-473 
27. Ang TL, Li JW, Wang LM. Endoscopic Ultrasound-Guided Tissue Acquisition in the Era of Precision Medicine. Journal of Gastroenterology and Hepatology. 2023; 38(10):1677-1678 
28. Leong JWH, Wang LM, , Ang TL, Kwek BEA, Ong JPL.Cronkhite-Canada Syndrome MasquerLi JWading as Inflammatory Bowel Disease.ACG Case Reports Journal. 2023; 10(9):e01090 
29. Tee CHN, R Rajesh, Ang TL, Li JW. Role of Artificial Intelligence in Barrett’s EsophagusArtificial Intelligence in Gastroenterology. 2023; 4(2):28-35 
30. Tan TC, Roslan NEB, Li JW, Zou X, Chen X, Ratnasari, Santosa A. Patient Acceptability of Symptoms Screening and Patient Education Using a Chatbot for Autoimmune Inflammatory Diseases: Survey Study. JMIR Formative Research. 2023; 7:e49239 
31. Li JW, Wang LM, Ang TL.Artificial Intelligence-assisted Colonoscopy: A Narrative Review of Current Data and Clinical Applications.Singapore Medical Journal. 2022; 63(3):118-124 
32. Chen E, Li JW, Wang LM, Lwin KY, Tan CK, Ong J, Ang TL. Lessons of the month 1: When What You See is not UC (Ulcerative Colitis): An Unusual Presentation of Pancolitis in a Developed Country. Clinical Medicine (London). 2022; 22(2):166-168 
33. Ang D, Koo SH, Chan YH, Tan TY, Soon GH, Tan CK, Lin KW, Krishnasamy-Balasubramanian JK, Wong YJ, Kumar R, R R, Tan Y, Ong PJ, Tan YJ, Li JW, Kwek AB, Ang TL. Clinical Trial: Seven-day Vonaprazan Versus 14-day Proton Pump Inhibitor-based Triple Therapy for First-line Helicobacter pylori Eradication. Alimentary Pharmacology & Therapeutics. 2022; 56(3):436-449
34. Namasivayam V, Koh CJ, Tsao S, Lee J, Ling KL, Khor C, Lim T, Li JW, Oo AM, Yip BCH, Hussain I, Chua TS, Toh BC, Ong HS, Wang LM, So JBY, Teh M, Yeoh KG, Ang TL.Academy of Medicine, Singapore guideline on endoscopic surveillance and management of gastric premalignant lesions. Annals of Academy of Medicine Singapore. 2022 Jul; 51(7):417-435 
35. Ang TL, Lim JF, Chua TS, Tan KY, Li JW, Cong CH, Gwee KA, Namasivayam V, Vu CKF, Khor CJL, Wang LM, Yeoh KG. Clinical Guidance on Endoscopic Management of Colonic Polyps in Singapore. Singapore Medical Journal. 2022; 63(4):173-186 
36. Ang TL, Seet E, Goh YC, Ng WK, Koh CJ, Lui HF, Li JW, Oo AM, Lim KBL, Ho KS, Chew MH, Quan WL, Tan DMY, Ng KH, Goh HS, Cheong WK, Tseng P, Ling KL.Academy of Medicine, Singapore Clinical Guideline on the Use of Sedation by Non-Anaesthesiologists during Gastrointestinal Endoscopy in the Hospital SettingAnnals of Academy of Medicine Singapore. 2022; 51(1):24-39 
37. Tan CK, Wang LM, Goh L, Li JW, Lin J, Ang TL.Tis not a Leiomyoma! Two Cases of Postendoscopic Full-thickness Resection Leiomyomatous Pseudopolyps. American Journal of Gastroenterology. 2022; 117(2):352-354   
38. Li JW, Chia TS, Fock KM, Chong KDW, Wong YJ, Ang TL.Artificial Intelligence and Polyp Detection in Colonoscopy: Use of a Single Neural Network to Achieve Rapid Polyp Localization for Clinical Use.Journal of Gastroenterology and Hepatology. Dec 2021; 36(12):3298-3307. 
39. JW Li, TL Ang, 2021, Narrow-Band Imaging. Philip W.Y. Chiu, Yasushi Sano, Noriya Uedo, Rajvinder Singh in Endoscopy in Early Gastrointestinal Cancers, Volume 1, Springer Nature Singapore Pte Ltd. 
40. Li JW, Ang TL. Colonoscopy and Artificial Intelligence: Bridging the Gap or a Gap Needing to be Bridged? Artificial Intelligence in Gastrointestinal Endoscopy. 2021; 2(2): 36-49 
41. Tan CK, Li JW, Wang LM, Kwek ABE, Ang TL.Colorectal Endoscopic Full Thickness Resection: Initial Experience from a Tertiary Centre in Singapore. GastroHep. 2021; 3(5):298-306 
42. Wu CCH, Namasivayam V, Li JW, Khor CJ, Fock KM, Law NM, Wang LM, Ang TL.A Prospective Randomized Tandem Gastroscopy Pilot Study of Linked Color Imaging Versus White Light Imaging for Detection of Upper Gastrointestinal Lesions.Journal of Gastroenterology and Hepatology. Sep 2021; 36(9):2562-2567 
43. Chang PE, Tan CK, Cheah CC, Li W, Chow WC, Wong YJ. Validation of the Expanded Baveno-VI Criteria for Screening Gastroscopy in Asian Patients with Compensated Advanced Chronic Liver Disease.Digestive Diseases and Sciences 2021; 66(4):1343-1348 
44. Tan YY, Tay GSK, Li JW, Kwek ABE, Ang YL, Wang LM, Tan MTK. Clinical Features and Predictors of Dysplasia in Proximal Sessile Serrated Lesions. Clinical Endoscopy. Jul 2021; 54(4):578-588 
45. Wong YJ, Thurairajah PH, Kumar R, Tan J, Fock KM, Li W, Kwek A, Tan YB, Koh J, Lee ZC, Kumar LS, Teo EK, Ang TL.Efficacy and Safety of Sofosbuvir/Velpatasvir in a Real-world Chronic Hepatitis C Genotype 3 Cohort.Journal of Gastroenterology and Hepatology 2021; 36(5):1300-1308 
46. Fang SLW, Teo L, Loo CY, Li JW, Santosa A. Lessons of the month 2: Ocular Manifestations and Complications of Hepatitis C. Clinical Medicine (London) 2021; 21(4):e417-e419 
47. Tay SW, Li JW, Fock KM.Diet and Cancer of the Esophagus and Stomach. Current Opinion in Gastroenterology. Mar 2021; 37(2): 158-163    
48. Ang TL, Li JW, Vu CKF, Ho GH, Chang PE, Chong CH, Chua TS, Ong DEH, Yip BCH, Gwee KA.Chapter of Gastroenterologists Professional Guidance on Risk Mitigation for Gastrointestinal Endoscopy during COVID-19 Pandemic in Singapore.Singapore Medical Journal. Jul 2020; 61(7): 345-349 
49. Ang TL, Li JW. Endoscopic Ultrasound-guided Biopsy and Endoscopic Ultrasound-guided Gastrointestinal Anastomosis: A tale of twin cities.Journal of Gastroenterology and Hepatology. Aug 2020; 35(8): 1259-1260 
50. Chang JPK, Wong YJ, Yang WL, Lim KBL, Tan PS, Ho GH, Yip BCH, Li JW, Chong CH, Ong DEH, Chua TS, Vu CKF, Gwee KA, Ang TL, Tan CK.Chapter of Gastroenterologists Professional Guidance for Management of Patients with Liver Disease in Singapore during the COVID-19 PandemicSingapore Medical Journal. 2020; 61(12): 619-623 
51. Wong YJ, Tan M, Zheng Q, Li JW, Kumar R, Fock KM, Teo EK, Ang TL.A Systematic Review and Meta-analysis of COVID-19 associated Liver Injury.Annals of Hepatology. 2020; 19(6): 627-634 
52. Teh K, Tay SW, Chen K, Koh SJ, Wong YJ, Kwek ABE, Li JW, Fock KM, Teo EK, Ang TL, Tan M. Impact of Enhanced Personal Protective Equipment on Colonoscopy Performance during the COVID-19 PandemicEndoscopy International Open. 2020; 8(6):E809-E814 
53. Wong YJ, Chandrasekaran KR, Lin WK, Kumar R, Tan YJ, Teo EK, Ang TL, Li WJ, Thurairajah PH.Short-term and Long-term predictors of nosocomial Spontaneous Bacterial Peritonitis in Singapore.Singapore Medical Journal. Aug 2020; 61(8): 419-425 
54. Li JW, Ang TL, Wang LM, Tan TK, Fock KM, Teo EK.Endoscopic Submucosal Dissection of Colorectal Neoplasms: an Audit of its Safety and Efficacy in a Single Tertiary Centre in Singapore. Singapore Medical Journal. 2019; 60(10): 526-531 
55. Ang TL, Li JW, Kwek BEA, Thurairajah PH, Wang LM.The Difference in Histological Yield between 19G EUS-FNA and EUS-fine Needle Biopsy Needles. Endoscopic Ultrasound 2019; 8(4): 255-260 
56. Ang TL, Li JW, Wong YJ, Tan YL, Fock KM, Tan TK, Kwek BE, Teo EK, Ang SH, Wang LM.A Prospective Randomised Study of Colonoscopy Using Blue Laser Imaging and White Light Imaging in the Detection and Differentiation of Colonic PolypsEndoscopy International Open. 2019; 7(10):E1207-E1213 
57. Wu C, Li JW, Ng KS, Ang D. Management of PEG Site Gastric Ulcer in a Patient with an Esophageal Stricture and Hiatus Hernia.Clinical Endoscopy. 2018; 51(1): 99-102 
58. Li JW, Ang TL, Kwek BE, Harichander PT, Fock KM, Teo EK.The Learning Curve for Needle Knife Precut Sphincterotomy Revisited.United European Gastroenterology Journal. 2017; 5(8): 1116-1122 
59.  Li JW, Goh BB, Chang PK, Tan CK.Barcelona Clinic Liver Cancer Outperforms Hong Kong Liver Cancer Staging of Hepatocellular Carcinoma in Multiethnic Asians – Real-World Perspective. World Journal of Gastroenterology. 2017; 23(22): 4054-4063 
60. Goh BB, Li JW, Chang PE, Lin YC, Chow KY, Tan CK.Deciphering the Epidemiology of Hepatocellular Carcinoma through the Passage of Time: a Study of 1401 Patients Across Three DecadesHepatology Communications. 2017; 1(6): 564-571 
61. Seo KI, Yun BC, Li WJ, Lee SU, Han BH, Park ET.Barriers to Treatment of Failed or Interferon Ineligible Patients in the Era of DAA: Single Center StudyClinical and Molecular Hepatology. 2017; 23(1): 74-79 
62. Li JW, Khor JC.Testing and Treating Helicobacter Pylori InfectionThe Singapore Family Physician. 2017; 43(2): 52-54 
63. Li JW, Ang TL.Is Direct Endoscopic Necrosectomy the Way to Go.Gastrointestinal Intervention. 2016; 5: 193-198 
64. Ang TL, Kwek BE, Song MJ, Li JW, Harichander PT.A Comparative Study of Strategies for Prevention of Post-ERCP Pancreatitis after Early Precut Sphincterotomy for Biliary Access.Journal of Digestive Diseases. 2016; 17(10):692-696 
65.  Li JW, Tan MT, Ang TL, Teo EK.Chemoprevention Trials of GI Cancers in Asia.Best Practice and Research: Clinical Gastroenterology. 2015; 29(6): 967-78 
66. Chang PE, Wong GW, Li JW, Lui HF, Chow WC, Tan CK.Epidemiology and Clinical Evolution of Liver Cirrhosis in Singapore.Annals of Academy of Medicine Singapore. 2015; 44(6): 218-25