Enzalutamide

Uses

Precaution

Side Effects

Handling

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Uses

What is Enzalutamide for?

Enzalutamide is a medicine that is used to treat metastatic prostate cancer (cancer that has spread beyond prostate gland). It works by blocking the effects of male sex hormones called androgens. Androgens may increase the growth of cancer cells.

How should I take or use Enzalutamide?

Enzalutamide is a capsule, to be taken by mouth once a day at the same time every day. Swallow whole and take the exact number of capsules as instructed by your doctor.

It can be taken with or without food, with a glass of water or juice.

What should I do if I forget to take or use Enzalutamide?

If you miss a dose, take it as soon as you remember. However if it is near to your next dose, skip the missed dose and resume your usual dosing time. Do not take double dose.

Precaution

What precautions should I take when taking or using Enzalutamide?

Inform your doctor or pharmacist if you:

Are on any other medicines e.g. warfarin
Have any other medical conditions e.g. heart problems, high blood pressure, history of seizures or epilepsy.

Use effective birth control during treatment and for at least 3 months after stopping treatment.

Side Effects

What are some common side effects of Enzalutamide?

Muscle, bone or joint pain
Feeling tired or weak
Swelling of your hands or feet
Headache or dizziness
Increased blood pressure
Hot flushes

If this occurs, take the tablet at bedtime. If night sweats interfere with sleep, try taking the tablet in the morning.

Decreased appetite
Diarrhea or constipation may occur

Inform your doctor if any of the following occurs:

Skin rashes, hives or itching
Shortness of breath or difficulty in breathing
Confusion or falling
Fast or irregular heartbeat
Seizures
Side effects become severe

Handling

How should I store Enzalutamide?

Keep away from children
Keep in a cool, dry place, away from direct sunlight
Store at room temperature

How should I handle Enzalutamide safely?

Do not chew, open or crush the capsules.

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What should I do if I overdose?

If you overdose on this medicine, inform your doctor immediately.

Disclaimers

Please take note that the above is not a complete list of all possible side effects. If you have any concerns about your medication or if you have other side effects that you think are caused by this medication, please consult your doctor or pharmacist.

If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.

This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System, and SingHealth), community pharmacies (Guardian, Unity, and Watsons), and the Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.