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Pertuzumab

Drug Class: Commonly Known As: Category:
Anti-HER2 Monoclonal Antibody Perjeta® Cancer-related

Pertuzumab - What is it for

Pertuzumab is used to treat HER2-positive breast cancer.
It is a monoclonal antibody which targets HER2, a certain type of protein on the surface of cancer cells, to control their growth.

Pertuzumab - Side Effects, Precautions, and Contraindications

What side effects can Pertuzumab cause?

  • Feeling tired and lack of energy
    • Do not drive or operate heavy machinery when you feel tired
  • Flu-like symptoms e.g. headache, weakness, mild fever (<38° C)
If you experience any of the following symptoms, you should inform your healthcare professional immediately.
  • Heart problems. Your doctor may arrange for a test to check your heart function once every few months while you are on this treatment. Symptoms of this include:
    • Persistent cough, shortness of breath or difficulty breathing
    • Swelling of hand or leg
  • Flu-like symptoms that worsen or do not go away
  • Allergic reactions. Please alert your nurse if you experience allergic reactions during your treatment. The symptoms of this include one or more of the following:
    • Chills, rigors
    • Facial flushing
    • Swollen face/eyes/lips/tongue
    • Difficulty in breathing
    • Itchy skin rashes over your whole body

Before taking Pertuzumab, what precautions must I follow?

​Inform your healthcare professional if:

  • You are allergic to this medication or any of the other ingredients of this medication.
  • You are pregnant or planning for pregnancy.
    • You should use effective birth control during treatment and for 7 months after your last treatment.
  • You are breastfeeding.
    • Do not breastfeed during treatment and for 7 months after your last treatment.
  • You are taking any other medications, including supplements, traditional medications and herbal remedies.

What food or medicine must I avoid when I take Pertuzumab?

Pertuzumab - Dosage and How to Use

How should Pertuzumab be used?

It is given as an injection into your vein (intravenous).

What should I do if I miss a dose?

What should I do if I overdose?

Pertuzumab - Handling

How should I handle Pertuzumab safely?

Pertuzumab - Storage

How should I store Pertuzumab?

How should I dispose of Pertuzumab safely?

Pertuzumab - Additional Information

  • Updated on Monday, November 30, 2020
  • Article contributed by PSS National Medication Information Workgroup PSS National Medication Information Workgroup

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

    ​​​​​​The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.

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