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Department of Pathology

Synonym(s):

Sengkang General Hospital's Department of Pathology offers a comprehensive range of clinical and diagnostic laboratory services, providing vital information to clinicians for the diagnosis, treatment, and prevention of various diseases. Our team of expert pathologists and laboratory scientists works closely with clinical colleagues to ensure exceptional patient care. Policies and procedures are in accordance with current best practices and regulatory requirements, ensuring the highest quality of services.

 

Laboratory Tests Offered

 

The Department of Pathology uses state-of-the-art equipment to offer a comprehensive range of laboratory tests.

Sub-Specialities Description Test(s) Performed
Anatomical Pathology

Anatomical pathology is a field of medicine that focuses on studying organs and groups of cells within the body. It plays a crucial role when doctors take tissue samples from patients for analysis in a laboratory. Anatomical pathologists provide definitive diagnoses based on these samples, which helps clinicians give the most effective advice and treatment.

There are two main subdivisions in anatomical pathology. Histopathology involves microscopic examination of samples taken from whole tissues, often enhanced by special staining techniques and associated tests. Cytopathology, or cytology, focuses on studying individual cells. It is used to diagnose various conditions and diseases.

Histopathology

  1. Routine surgical biopsies
  2. Frozen section
  3. Specialised biopsies such as Renal biopsies, Bone marrow trephine biopies, Gastrointestinal biopsies, Liver biopsies etc
  4. Immunofluorescence for renal and skin cases
  5. Immunohistochemistry

Cytopathology

  1. Gynaecological Cytology (Conventional Cervical Pap Smear and Liquid-based Gynaecological Cytology)
  2. Non-Gynaecological Cytology (e.g., sputum, urines, peritoneal/ pleural fluid, lavages)
  3. Fine Needle Aspiration Cytology
  4. Identification of infections and associated organisms including bacteria, fungi, protozoa and viruses.
  5. Evaluation of joint aspirates
Body Fluids & Miscellaneous Laboratory testing which involves different techniques, such as microscopic examination and chemical analysis, can be used on other body fluids besides blood. These methods offer additional insights to complement information from blood tests, leading to a better understanding of a patient's health. By examining various body fluids, healthcare professionals gain a more holistic view of the body's internal processes, aiding in accurate diagnosis and treatment of medical conditions.
  1. Urine Full Examination Microscopic Examination (UFEME)
  2. Urine Dipstick Analysis
  3. Urine Phase Contrast Microscopy
  4. Cerebrospinal Fluid Analysis
  5. Pleural Fluid Analysis
  6. Peritoneal Fluid Analysis
  7. Synovial Fluid Analysis
  8. Dengue Screen (Antigen testing, IgG and IgM Screen)
  9. Helicobacter Pylori Rapid Screen Test
Blood Banking & Transfusion Medicine

The Blood Banking & Transfusion Medicine section provides various blood components like red cells, platelets, plasma, and cryoprecipitate, as well as, purified plasma-derived blood products. These are used for routine transfusions and emergency situations such as severe bleeding. The hospital keeps a ready supply of blood for emergencies.

To ensure safe transfusions, the section provides round-the-clock testing, which includes determining blood types (like ABO and Rh), checking for antibodies that could affect transfusion safety, and testing compatibility between donor and patient blood. They also investigate transfusion reactions and perform specialised tests for complex conditions before sending samples to national reference laboratories. The hospital blood bank assists SKH Blood Transfusion Committee to oversee transfusion quality and safety through audits and quality monitoring.

  1. ABO Grouping and RhD typing
  2. Red cell antibody screening
  3. Direct Coombs Test
  4. Cross Match Compatibility Testing
  5. Transfusion Reaction Workup
  6.  Clotting Factor Provision Workflow for ROTEM-guided Coagulation Product Replacement
  7. Rapid blood delivery to critical care areas by hospital pneumatic tube system

Clinical Biochemistry

The Clinical Biochemistry section offers 24-hour services for analysing the biochemical components present in blood, urine, cerebrospinal fluid, and other body fluids. This comprehensive service encompasses a diverse array of tests providing valuable insights into the physiological and pathological conditions of patients, all aimed at supporting clinicians in the accurate diagnosis and effective management of a wide spectrum of diseases.

  1. Renal Function Tests
  2. Liver Function Tests
  3. Thyroid Function Tests
  4. Cardiac Markers
  5. Lipid Panel
  6. Anaemic Panel
  7. Tumour Markers
  8. Inflammatory Markers
  9. Hormones
  10. Blood Ketones
  11. Glucose Tolerance Test
  12. HbA1c
  13. Therapeutic Drug Monitoring
  14. Arterial Blood Gases
  15. HIV and Hepatitis Screen
Microbiology

The Microbiology section offers a 24/7 service for the diagnosis of clinically relevant acute and chronic infections. A wide range of assays spanning bacteriology and mycology are performed on a combination of automated platforms and manual systems, to provide a comprehensive infection science service. In addition, the laboratory offers microbial surveillance tests on both clinical and environmental samples.

Tests offered:

  1. Bacteriology (Microscopy, culture and susceptibility testing)
  2. Mycology (Identification for Candida species)
  3. Mycobacteriology (Microscopy)

Sample types:

  1. Blood (in blood culture bottles)
  2. Fluid samples (both sterile and non-sterile sites)
  3. Tissue samples
  4. Respiratory tract samples
  5. Urine
  6. Stool
  7. Environmental samples
  8. Prosthetic devices (from sterile sites)
  9. Nosocomial infection screening
Haematology

The Haematology section plays a critical role by offering essential services such as routine analysis of blood cells, evaluating blood clotting functions, and screening for parasites that can be transmitted through the blood. These services are crucial for diagnosing various blood-related disorders and ensuring timely treatment.

Haematology

  1. Full blood count
  2. Erythrocyte Sedimentation Rate (ESR)
  3. Blood Film Report
  4. Blood for Malaria Parasite
  5. Blood for Microfilaria
  6. Reticulocyte Count

Coagulation

  1. Prothrombin Time (PT) and INR
  2. Activated Partial Thromboplastin Time (APTT)
  3. D-Dimer Test (Quantitative)
  4. Fibrinogen Test
  5. Thrombin Time (TT)
Molecular Diagnostics

The Molecular Diagnostics section offers routine and rapid molecular tests for the detection of a repertoire of infectious agents, monitoring of viral loads, and genotyping of viruses.

In addition, the laboratory also offers tests for pharmacogenetics and oncogene mutations.

  1. Candida auris PCR
  2. COVID-19 PCR
  3. CYP2C19 Genotyping
  4. Gastrointestinal (GI) Panel PCR
  5. Hepatitis B Virus PCR
  6. Hepatitis C Virus PCR
  7. HPV Genotyping
  8. MERS Coronavirus & Respiratory Panel PCR
  9. MRSA PCR
  10. Next-generation sequencing for tumour mutations
  11. Respiratory Panel Multiplex PCR

Our Care Team

News

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