Pegasys - Side Effects, Precautions, and Contraindication
Skip Ribbon Commands
Skip to main content

Pegylated Interferon alpha-2a

Drug Class: Commonly Known As: Category:
Interferon Alfa (2a) Pegasys™ Adult

Pegylated Interferon alpha-2a - Side Effects, Precautions, and Contraindications

What side effects can Pegylated Interferon alpha-2a cause?

Appears within hours to days after taking interferon

  1. Flu-like symptoms (fever, headaches, muscle aches, fatigue)
  2. Weakness
  3. Bone pain
  4. Psychiatric problems (subtle mood changes or a depressed mood that may affect a person's emotional state and social life)
  5. Occasional patients may experience major depression
  6. Skin reactions – injection site reactions; red, itchy rash

Appears within weeks to years after taking interferon

  1. Nausea, abdominal pain, diarrhoea
  2. Hair loss
  3. Autoimmune disorders e.g. thyroid problems
  4. Abnormal liver function blood test results

Stop taking interferon and consult your doctor if you develop the following problems:

  1. Severe depression (significant low mood, thoughts of hurting yourself)
  2. Severe abdominal pain
  3. High fever (>38°C)
  4. Abnormal bleeding or bruising
  5. Changes in your vision
  6. Chest pain or breathlessness

Before taking Pegylated Interferon alpha-2a , what precautions must I follow?

What food or medicine must I avoid when I take Pegylated Interferon alpha-2a ?

Pegylated Interferon alpha-2a - Additional Information

​If you are pregnant or planning to become pregnant, inform your doctor. If you wish to breastfeed, the pros and cons should be discussed with your doctor. Although interferon is excreted in breastmilk, the levels of interferon in breastfed babies whose mothers are on interferon are not increased.

  • Updated on 5/15/2019 12:00:00 AM
  • Article contributed by Singapore General Hospital
The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

Find Your Medicines