Lim Shih Hui
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Prof Lim Shih Hui

Prof Lim Shih Hui

MBBS, M Med (Int Med), MRCP (UK), FAMS (Neurology), FRCP (Edin)​​​, FRCP, FRACP(Hon), FACP(Hon), MBA

Senior Consultant

National Neuroscience Institute

Specialty: Neurology

Clinical Interest: Epilepsy, General Neurology, Clinical Neurophysiology

Conditions Treated by this Doctor:

Clinical Appointments

  • Senior Consultant Department of Neurology National Neuroscience InstituteNational Neuroscience Institute
  • Senior Consultant Neurology Singapore General HospitalSingapore General Hospital


Professor Lim has contributed significantly in the field of neurology, epilepsy, education and medical professional organizations, in Singapore and the region.  He has organized numerous neurology, epilepsy and EEG teaching courses and workshops in Asia, including the International Epilepsy Congress and Asian Oceanian Epilepsy Congress.  He initiated an EEG Certification Examination in Asia in 2005, elevating the standard of EEG recording, interpretation and reporting in our region.  As Founding President of the College of Physicians Singapore (2004-2007). He created and grew 15 Internal Medicine-related specialty Chapters, contributing to the professional development of Internal Medicine in Singapore and the region.  As Master of Academy of Medicine, Singapore (2012 to 2016) developed Academy professionally and academically into a cohesive specialists’ organization with 13 Colleges representing all medical and dental specialties in Singapore.  He also initiated collaborations with MOH of Brunei Darussalam and Maastricht University, built financial capabilities and conferred academy’s fellowship to specially trained family medicine physicians in Singapore.  As the Co-Chair of the Joint Committee on Specialist Training of the Specialist Accreditation Board of the MOH Singapore, he oversaw the training, assessment, and accreditation of training programmes of 35 medical specialties and 6 subspecialties.  He is one of the few Western doctors who received training in Acupuncture and now contributing in the governance and professional development of Traditional Chinese Medicine in Singapore.

He served as Group Director for Education at Singapore Health Services (2015-2017), overseeing the medical, dental, nursing, and allied health’s under-graduate and postgraduate health profession education.  He integrated more than 20 independent educational entities within SingHealth and transformed them into a comprehensive Educational Enterprise – SingHealth Academy with 5 Health Profession Colleges (College of Allied Health, College of Clinical Dentistry, College of Clinical Medicine, College of Clinical Nursing, and College of Healthcare Administration and Leadership) and 1 simulation institute (SingHealth Duke-NUS Institute of Medical Simulation). These Colleges are now providing better coordinated education pathway across the continuum – from undergraduate, graduate, postgraduate to continuing professional education.  This integration has created more synergy within each profession as well as increased opportunities to foster closer collaboration across various institutions, further enhancing inter-professional education which is vital for inter-professional collaborative practice.


Master of Business Administration, National University of Singapore, 2001-2002

Acupuncture, Singapore Acupuncture Association, 1997-1999

Clinical Fellowship in Epilepsy and Clinical Neurophysiology, Cleveland Clinic Foundation, 1989-1991

Advance Specialist Training in Neurology, Singapore General Hospital and Tan Tock Seng Hospital, 1987-1989

Basic Specialist Training in Internal Medicine, Ministry of Health, Singapore, 1985-1987

Bachelor of Medicine and Bachelor of Surgery, National University of Singapore, 1977-1982

Professional Appointments and Committee Memberships

  • Senior Consultant, Department of Neurology, National Neuroscience Institute (NNI@SGH)
  • Chairman, JCST Accreditation Committee, Ministry of Health (2016 – date)
  • Member, Traditional Chinese Medicine Practitioner Board, Ministry of Health (2016 – date)
  • Chairman, ASEPA-ASNA EEG Certification Examination Board (2004 – date)
  • Dean, Academy of Medicine, Singapore Deanery (2016—date)
  • Group Director, Education, SingHealth (2015-2017)
  • Master, Academy of Medicine, Singapore (2012-2016)
  • Co-Chairman, Joint Committee on Specialist Training, Specialist Accreditation Board, Ministry of Health (2012-2016)
  • Chairman, Asian Epilepsy Academy (2011-2015)
  • Chairman, Commission on Asian Oceanian Affairs, International League Against Epilepsy (2005-2009)
  • President, College of Physicians, Singapore (2004-2007)
  • President, ASEAN Neurological Association (2003-2007)
  • Chairman, Chapter of Physicians, Academy of Medicine, Singapore (2002-2004)
  • Vice-Chair, Acupuncture Research Committee, Ministry of Health (1996-2001)
  • Chairman, ASEAN Neurological Association (1995-1997)
  • President, Clinical Neuroscience Society (1995-1997)
  • Professor and Senior Associate Dean, Office of Academic and Clinical Development, Duke-NUS Medical School
  • Adjunct Professor, Lee Kong Chian School of Medicine, NTU


  • National Medical Excellence Award: National Outstanding Clinician Educator Award, 2015
  • Singapore Health Service Excellence Award: Distinguish Educator Award, 2011
  • International League Against Epilepsy - Ambassador for Epilepsy, 2007

Research Interests


  • Lim SH, Chee KT: Schizophrenia-like psychosis with Capgrass syndrome in a patient with right temporal lobe epilepsy. Singapore Med J 1985;26:490-3.
  • Lim SH, Puvan K: Intra-medullary spinal cord metastasis. Ann Acad Med Singapore 1989;18:324-5.  
  • Lim SH, Puvan K, Cheah ES: A case of sarcoidosis presenting as cranial polyneuritis. Singapore Med J 1989;30:400-3.
  • Lim SH, Wong MC, Puvan K: Syringomyelia with Arnold Chiari I malformation: a report of four cases. Singapore Med J 1989; 30(4):376-9.  
  • Lim SH, Tan CB, Chan KM, Tjia HTL: Acute sympathotonic orthostatic hypotension with recovery. Ann Acad Med Singapore 1990;19:404-6.  
  • Lim SH, Heng LK, Puvan K: Secondary syphilis presenting as peri-optic neuritis and uveitis. Ann Acad Med Singapore 1990;19:413-5.  
  • Lim SH, So NK, Lüders H, Morris HH, Turnbull J: Etiological factors for unitemporal versus bitemporal epileptiform discharges. Arch Neurol 1991;48:1225-8.   
  • Lim SH, Pillay P, Lüders H, Boenigk H: Use of intracrnial neurophysiologic recording techniques in the evaluation of epilepsy surgery in children. Singapore Med J, 1992;33:131-8.  
  • Wong MC, Ng ISL, Lim SH: Huntington's disease in 5 siblings.  Ann Acad Med Singapore 1993; 22 (Suppl 3): 428-30  
  • Chee MWL, Lim SH, Tjia HTJ: Computed tomography in patients with recurrent seizures.  Ann Acad Med Singapore 1993; 22 (Suppl 3): 431-4.  
  • Pillay PK, Lim SH, Chee M, Awad I, Lüders HO: Epilepsy surgery in children and adult.  Ann Acad Med Singapore 1993; 22 (Suppl 3): 501-12.  
  • Lim SH, Diner DS, Pillay PK, Lüders HO, Morris HH, Klem G, Wyllie E, Awad, IA: Functional anatomy of the human supplementary sensorimotor area -- results of extraoperative electrical stimulation.  Electroencephalograhy and Clinical Neurophysiology 1994;91:179-193  
  • Steinhoff BJ, So NK, Lim SH, Lüders HO: Ictal scalp EEG in temporal lobe epilepsy with unitemporal versus bitemporal interictal epileptiform discharges. Neurology  1995;45:889-896  
  • Lim SH, Dinner DS, Lüders HO: Cortical Stimulation of the supplementary sensorimotor area.  In: Lüders HO eds.  The supplementary sensormotor area. New York; Raven Press.  Advances in Neurology, 1996; Vol 70:187-97  
  • Lim SH, Tan CH: Spectrum of Neurological Diseases in Singapore.  Neurol J Southeast Asia, 1996, 1:19-26  
  • Lim SH, Dinner DS, Lüders HO: Electrical stimulation of the mesial hemispheric cerebral cortex in human.  In  Kimura J,  Shibasaki H eds.  Recent advances in clinical neurophysiology, Elsevier, 1996;99-104
  • Lim SH, Tan EK, Chen C: Pattern of anti-epileptic drug usage in a tertiary referral hospital in Singapore.  Neurol J Southeast Asia, 1997;2:77-85  
  • Tan EK, Lim SH, Lim W, Tan KP: MRI in patients with chronic partial epilepsy: identification of potential epilepsy surgery candidates.  Neurol J Southeast Asia 1997;2:37-43  
  • Tan CT. Lim SH: Epilepsy in South East Asia.   Neurol J Southeast Asia 1997;2:11-15  
  • Yip SKH, Cheng C, Wong MYC, Tan BH, Sim CS, Lim SH: Cryptococcal prostatic abscess in an immunocompromised patient: a case report and review of the literature. Ann Acad Med Singapore 1998;27:873-6   
  • Tan EK, Lim SH, Chan LL, Wong ZW: Trigeminal neuralgia: should MRI be done routinely? Aust N Z J Med 1998 Dec;28(6):827-9  
  • Tan EK, Ng I, Law HY, Zhao Y, Wong MC, Chan LL, Lim SH, Chen C, Tan KP, Wong ZW: Machado-Joseph Disease/Spinocerebellar Ataxia 3 -- A Clinical, Imaging and Genetic Study in 3 Chinese Families. Neurol J of Southeast Asia 1998;3:61-67.  
  • Yong D, Lim SH, Zhao CX, Cui SL, Zhang L, Lee TL: Acupuncture treatment at Ang Mo Kio Community Hospital: a report on our initial experience.  Singapore Med J 1999;40(4):260-4  
  • Tan EK, Chan LL, Lim SH, Lim WEH, Khoo JBK, Tan KP: Role of magnetic resonance imaging and magnetic resonance angiography in patients with hemifacial spasm.  Ann Acad Med Singapore, 1999;28: 169-73   
  • Tan EK, Lim SH, Wong MC, Chan LL: Facial diplegia: cranial variant of Guillain Barre Syndrome? J R Soc Med 1999;92:26-27.    
  • Tan EK, Lim SH, Chan LL, Wong MC, Tan KP: X-linked adrenoleukodystrophy – spinocerebellar variant.  Clinical Neurology and Neurosurgery, 1999; 10:137-40   
  • Pan ABS, Lim SH: Public awareness, attitudes and understanding toward epilepsy among Singaporean Chinese.  Neurol J Southeast Asia 2000; 5:5-10  
  • Lim EC, Lim SH, Wilder-Smith E: Brain seizes, heart ceases: a case of ictal asystole. J Neurol Neurosurg Psychiatry 2000;69(4):557-9   
  • Dinner D, Luders HO, Lim SH: Supplementary sensorimotor area: Human: SMA proper.  In Luders HO & Noachtar S eds.  Epileptic Seizures: pathophysiology and Clinical Semiology. New York; Churchill Livingstone Inc, 2000: 192-198
  • Lim SH, Wilder-Smith, Pan ABS, Puvanendran K: Seizures and epilepsy – diagnosis, investigation and treatment in adults.  In: Ong YY eds.  A Clinical Approach To Medicine. 2001
  • Sakamoto A, Benbadis S, Godoy J, Ikeda A, Lee BI, Lim SH, Noachtar S, Palmini A, Pomata H, Tuxhorn I, Villarejo F: Essential for the establishment of a surgery of epilepsy program. In: Lüders HO eds.  Epilepsy Surgery.  Lippincott Williams & Wilkins.  2001
  • Wilder-Smith E, Lim SH: Heart rate changes during partial seizures – a study amongs Singaporean patients.  BMC Neurology 2001(12),1:5 
  • Tan EK, Chan LL, Lum SY, Koh P, Han SY, Fook-Chong S, Lo YL, Pavanni R, Wong MC, Lim SH: Is Hypertension associated with Hemifacial Spasm? Neurology 2003;60;343-344.  
  • Erle Lim, YS Wong, YL Lo, SH Lim, Traumatic Atypical Brown-Sequard Syndrome: Case Report And Literature Review. Clin Neurol Neurosurg 2003;105(2)143-145  
  • Leong SS, Tan EH, fong KW, Wilder-Smith E, Ong YK, Tai BC, Chew L, Lim SH, Wee J, Lee KM, Foo KF, Ang P, Ang PT:  Randomized double-blind trial of combined modality treatment with or without amifostine in unresectable stage III non-small cell lung cancer.  J Clin Oncol 2003; 21(9): 1767-1774  
  • Chia YC, Lim SH, Wang SJ, Cheong YM, Denaro J, Hettiarachchi J: Efficacy of eletriptan in migraine patients with persistent poor response to NSAIDs.  Headache 2003;43:984-990
  • Nurjannah S, Pan ABS, Lim SH: Semiology of non-epileptic seizures in Singapore patients. Neurology Asia 2004; 9(Supplement 1): 101-102 
  • Dan YF, Pan ABS, Lim SH: Periodic lateralized epileptiform discharges – etiology and association with EEG seizures.  Neurology Asia 2004; 9(Supplement 1): 107-108 
  • E Lim, SH Lim, HL Teoh, E Wilder-Smith: Frontal lobe tumor masquerading as nocturnal frontal lobe epilepsy: case report and review of the literature.  Case Rep Clin Pract Rev 2004; 5(null):CS446-449 
  • Chua TS, Lim SH, Oh VM:  Bridging the gap between physician specialists: a role for the College of Physicians, Singapore. Ann Acad Med Singapore. 2005 Oct;34(9):531-2  
  • Lim SH, Pan A: Attitudes, and perceptions of epilepsy in Asia: toward a uniform study protocol. Epilepsia. 2005;46 Suppl 1:48-9 
  • Ho YC, Goh KY, Golay X, Hong WT, Lim SH, Pan AB, Chua VG, Hui F, Sitoh YY: Functional magnetic resonance imaging in adult craniopagus for presurgical evaluation. J Neurosurg. 2005 Nov;103(5):910-6 
  • Lim SH, Wilder-Smith, Pan ABS, Puvanendran K: Seizures and epilepsy: diagnosis, investigation and treatment in adults.  In: Ong YY eds.  A Clinical Approach To Medicine. 2005
  • Wilder-Smith, Wong MC, Lim SH, Pavanni: Headaches. In Ong YY eds. A Clinical Approach To Medicine.  2005
  • H Parmar, SH Lim, NCK Tan, TCC Lim: Acute symptomatic seizures and hippocampus damage: DWI and MRS findings.  Neurology 2006;66:1–3 
  • Lim SW, Zhao Y, Chua E, Law HY, Yeun Y, Pavanni R, Wong MC, Ng IS, Yoon CS, Puong KY, Lim SH, Tan EK: Genetic Analysis of SCA2, 3 and 17 in idiopathic Parkinson’s disease. Neuroscience Letters 2006;403:11-14 
  • Jamora D, Lim SH, Pan A, Tan L, Tan EK: Valproate-induced parkinsonism in epilepsy patients.  Mov Disord 2007;22:130-3 
  • De Silva DA, Lim SH, Tan EK: Persistent hand spasm – movement disorder or seizure?  J Neurol  Sci 2007;252:185-8. 
  • Lim SH, Tan CT: Training and Certification of neurologists in South East Asia.  Neurology Asia 2007; 12 : 47 – 52 
  • Chan LL, Sitoh YY, Chong J, See SJ, Umapathi TN, Lim SH, Ong B: Application of the McDonald MRI criteria in multiple sclerosis.  Ann Acad Med Singapore. 2007;36(8):647-54 
  • De Silva DA, Pan AB, Lim SH.  Cefepime-induced encephalopathy with triphasic waves in three Asian patients.  Ann Acad Med Singapore. 2007;36(6):450-1 
  • Lim SH, Ng KY, Chew CH: From the Chapter of Physicians, Academy of Medicine to College of Physicians, Singapore.  Ann Acad Med Singapore 2007;36:525-540 
  • Lim SH. History of Epilepsy Surgery in Southeast Asia.  In: Lüders HO eds.  Textbook of Epilepsy Surgery, Informa Healthcare, 2008: 130-3
  • Kwan P, Lim SH, Chinvarun Y, Cabral-Lim L, Abdul Aziz Z, Lo YK, Tonner R, Beh K, Edrich P: Efficacy and safety of levetiracetam as adjunctive therapy in adult patients with uncontrolled partial epilepsy: the Asia SKATE II Study.  Epilepsy and Behaviour. 2010;18(1-2):100-5 
  • SL Cui, KH Tan, SH Subner, PC Xu, SH Lim, YY Huang, YY, S Xu, HS Ng: Safety Culture in Acupuncture Practice in a Tertiary Hospital: The Singapore General Hospital Experience.  Medical Acupuncture.  2013;25(1):61-73 
  • Gosavi T Diong CP, Lim SH: Methotrexate-induced myelopathy mimicking subacute combined degeneration of the spinal cord.  J Clin Neurosci. 2013;20(7):1025-6. 
  • Gosavi TD, Ahmad MT, Lee LH, Lim SH.  Methotrexate induced leucoencephalopathy: A stroke mimic.  Ann Indian Acad Neurol. 2013;16(3):418-21 
  • Tan NC, Lim SH: Epilepsy – Looking beyond seizures. Ann Acad Med Singapore. 2013;42(3):108-
  • Kong ST, Lim SH, Chan E, Ho PC:  Estimation and comparison of carbamazepine population pharmacokinetics using dried blood spot and plasma concentrations from people with epilepsy – the clinical implication.  J Clin Pharmacol. 2014;54(2):225-33 
  • Kong ST, Lim SH, Lee WB, Kumar PK, Wang HY, Ng YL, Wong PS, Ho PC: Clinical validation and implications of dried blood spot sampling of carbamazepine, valproic acid and phenytoin in patients with epilepsy. PLoS One. 2014 Sep 25;9(9):e108190.  
  • Toh DSL, Tan LL, Aw DCW, Pang SM, Lim SH, Thirumoorthy T, Lee HY, Tay YK, Tan SK, Vasudevan A,  Lateef A, Chong YY , Chan YC, Loke C, Chan CL, Koay ESC, Ren EC, Lee EJD, Sung C: Building pharmacogenetics into a pharmacovigilance program in Singapore: using serious skin rash as a pilot study. Pharmacogenomics J. 2014; 14(4):316-21 
  • Cui SL, Tan KH, Ong BC, Lim SH, Yong Y, Seah CN, Huang Y, Han SN: Standardized management of acupuncture-moxibustion clinic in Singapore General Hospital. Zhongguo Zhen Jiu. 2014;34(2):179-82. 
  • Tan NC, Aw L, Khin LW, Thirumoorthy T, Lim SH, Tai BC, Goh LG: How do primary care physicians in Singapore keep healthy? Singapore Med J. 2014;55(3):155-9. 
  • Kong ST, Ho CS, Ho PC, Lim SH: Prevalence of drug resistant epilepsy in adults with epilepsy attending a neurology clinic of a tertiary referral hospital in Singapore, Epilepsy Research 2014;108(7):1253-62 
  • Gosavi TD, See SJ, Lim SH: Ictal and interictal EEG patterns in patients with nonconvulsive and subtle convulsive status epilepticus.  Epilepsy Behav. 2015;49:263-7 
  • Kwan P, Cabral-Lim L, D'Souza W, Jain S, Lee BI, Liao W, Lim SH, Otsuki T, Tan CT, Wantanabe M; CAOA Research Task Force Research: Priorities in epilepsy for the Asia-Oceanian region. Epilepsia. 2015;56(5):667-73

Research Trials