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Causes and Risk Factors
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Stomach Cancer - Causes and Risk Factors
While the exact cause of stomach cancer is unknown, several factors have been found to play a role in its development. These risk factors include:
A chronic infection by a bacteria called helicobacter pylori
Gastroesophageal reflux disease
A diet high in salted or preserved (cured/smoked/pickled) foods
A diet low in fruits and vegetables
Smoking and alcohol
Family history of stomach cancer
Hereditary syndromes such as familial adenomatous polyposis (FAP), Li-Fraumeni syndrome, hereditary nonpolyposis colorectal cancer (HNPCC) and Peutz-Jeghers syndrome
Medical conditions that may contribute to stomach cancer such as:
- Anaemia (megaloblastic anaemia and pernicious anaemia)
- Previous stomach operation with partial removal of the stomach (gastrectomy)
- A stomach disorder called atrophic gastritis, which results in lower than normal production of digestive juices
- Stomach polyps
These risk factors are more commonly seen in people who have stomach cancer. Having one or more of these risk factors does not mean that you will develop stomach cancer. Stomach cancer may still develop in patients with none of the above risk factors.
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Article contributed by
National Cancer Centre Singapore
;
Singapore General Hospital
;
Changi General Hospital
;
Sengkang General Hospital
;
KK Women's and Children's Hospital
The information provided is not intended as medical advice.
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