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Abiraterone

Drug Class: Commonly Known As: Category:
Antiandrogen Zytiga® Cancer-related

Abiraterone - What is it for

Abiraterone is a medicine given to patients with castrate-resistant prostate cancer. It works by decreasing the amount of androgens in your body and is usually given with prednisolone.

Abiraterone - Side Effects, Precautions, and Contraindications

What side effects can Abiraterone cause?

  • Joint and muscle pain and weakness
  • Swelling of the leg or feet
  • Hot flushes
  • Headache, giddiness
  • Diarrhea or heartburn
  • High blood pressure
  • Increased blood sugar levels

Inform your doctor if any of the following occurs:

  • Excessive giddiness, weakness, light-headedness or confusion
  • Severe headache
  • Severe muscle or joint pain
  • Severe leg or feet swelling
  • Fast or irregular heartbeat
  • Fever (>37.5°C) accompanied by flu-like symptoms
  • Pain on urination
  • Yellowing of the skin or eyes, or having dark tea-coloured urine

Before taking Abiraterone, what precautions must I follow?

  • Inform your doctor or pharmacist if you:
    • Are on any other medicines e.g. warfarin
    • Have any other medical conditions e.g. heart problems, high blood pressure
  • Use effective birth control during treatment and for at least 1 week after stopping treatment

What food or medicine must I avoid when I take Abiraterone?

Abiraterone - Dosage and How to Use

How should Abiraterone be used?

​It is a tablet taken by mouth, once daily on an empty stomach i.e. either 1 hour before or 2 hours after food. You may take it with a glass of water or juice.

What should I do if I miss a dose?

​If you miss a dose of Abiraterone, skip the missed dose and go back to your usual dosing time. Do not make up for the missed dose by taking 2 doses at once.

What should I do if I overdose?

If you overdose on this medicine, inform your doctor immediately.

Abiraterone - Handling and Storage

How should I handle Abiraterone safely?

Women of child-bearing potential should wear gloves while handling this medicine.

How should I store Abiraterone?

Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#Store at room temperature;#

How should I dispose of Abiraterone safely?

Abiraterone - Additional Information

  • Updated on Thursday, January 14, 2021
  • Article contributed by Department of Pharmacy National Cancer Centre Singapore, Singapore General Hospital

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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