Imiquimod - Side Effects, Precautions, and Contraindications
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Drug Class: Commonly Known As: Category:
Immune Modulator Aldara Adult, Children

Imiquimod - Side Effects, Precautions, and Contraindications

What side effects can Imiquimod cause?

Common side effects include:

  • Skin reddening, swelling and flakiness
    • These reactions are normal as they are signs of your immune system fighting the abnormal cells. Even if these symptoms are not present, the medication may still be working.
  • Formation of crust during healing
  • Itching
  • Burning sensation
  • Stinging
  • Lighter skin colour on the warts or around the warts

Should the skin reactions become too uncomfortable, remove the cream by washing with mild soap and water. Take a short break of 3 to 4 days before continuing it again. If any side effects persist or are severe, please consult your doctor.

Rare but serious side effects include:

  • Flu-like symptoms such as swollen lymph nodes, aches and pains, mild fever and may generally feel unwell

For genital or perianal warts

  • Vaginal pain or swelling
  • Difficulty passing urine
  • Severe tightness, swelling or skin tearing

If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.

Before taking Imiquimod , what precautions must I follow?

  • Avoid contact with the eyes, lips and nostrils.
  • Imiquimod cream administration is not recommended until the treatment area has healed from any previous drug or surgical treatment.
  • The treatment area should NOT be wrapped or covered with occlusive dressing.
  • For patients using it for external genital and perianal warts:
    • Sexual contact should be avoided while the cream is on the skin.
    • Imiquimod cream may weaken condoms and vaginal diaphragms, thus concurrent use is not recommended.
    • Not to be used in pregnant women. 

Inform your healthcare professional if:

  • You are allergic to this medication or any of the other ingredients of this medication.
  • You are pregnant, planning to become pregnant, or breastfeeding.

What food or medicine must I avoid when I take Imiquimod ?

  • Updated on 4/30/2021 12:00:00 AM
  • Article contributed by PSS National Medication Information Workgroup PSS National Medication Information Workgroup
The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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