Macitentan is used to treat pulmonary arterial
Every individual may respond to treatment in different
ways. It is important that patients have realistic
expectations of what the treatment can do.
It lowers the pressure in the pulmonary arteries (the blood
vessels that transfer oxygen from the lungs to the blood) by
blocking the effects of endothelin. It may have the potential
to reverse some of the damage done by the condition. This
should also improve symptoms such as breathlessness and
increase your ability to exercise.
Please inform your doctor if you are pregnant before
starting this medicine.
Macitentan is available as a 10mg tablet, to be taken
by mouth once per day.
Macitentan can be taken with or without food.
As this medication may cause birth defects, female
patients of childbearing age should take precautions
by using at least 2 reliable methods of contraception to
avoid pregnancy. If you suspect you may be pregnant,
inform your Cardiologist as soon as possible.
If you forget to take a dose, take it as soon as you
remember but do not take two doses at once.
Do not stop taking this medication suddenly without
informing your Cardiologist, Nurse and/or Pharmacist
as it may make your condition worse.
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