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Pazopanib

Drug Class: Commonly Known As: Category:
Multi-Kinase Inhibitor Votrient® Cancer-related

Pazopanib - Side Effects, Precautions, and Contraindications

What side effects can Pazopanib cause?

  • Nausea, decreased appetite
  • Diarrhea and/or abdominal pain
  • Discoloration of skin and hair
  • Increased risk of bleeding or bruising
    Inform your doctor if you have any surgery planned.
  • High blood pressure
    Monitor your blood pressure closely.
  • Tiredness and lack of energy

Inform your doctor if any of the following occurs:

  • Rapid or irregular heartbeat, or chest pain
  • Sudden onset of cough or shortness of breath
  • Unusual swelling of hands or feet
  • Yellowing of the eyes or skin, dark tea-colored urine
  • Prolonged bleeding or bruising, poor healing wounds
  • Severe headache, unusual weakness, tiredness or light-headedness
  • Severe diarrhea or abdominal pain
  • Signs of infection – fever of 38°C or higher, chills, sore throat, pain or difficulty urinating
    To minimize infection risk, avoid crowds or being near people with injection.

Before taking Pazopanib, what precautions must I follow?

  • Use effective birth control during treatment and for 2 weeks after stopping Pazopanib. Inform your doctor if you or your partner plan for or suspect pregnancy.
  • Do not take any medication and supplements without medical supervision.
  • Inform your doctor or pharmacist if you have any other medical conditions e.g. heart problems, high blood pressure, adrenal insufficiency, diabetes.

What food or medicine must I avoid when I take Pazopanib?

  • Grapefruit and its juice.

Pazopanib - Additional Information

  • Updated on Friday, March 1, 2019
  • Article contributed by Department of Pharmacy National Cancer Centre Singapore

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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