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Secukinumab - Side Effects, Precautions, and Contraindications

What side effects can Secukinumab cause?

​Side effects may occur when taking Secukinumab, but the vast majority of these tend to resolve spontaneously. Common side effects include:

  • Reaction at injection site such as swelling, itching or bruising. They usually subside within 3 to 5 days
  • Sore throat
  • Blocked/runny nose
  • Diarrhoea
  • Cold sores

Consult your doctor about any symptoms that becomes bothersome.

Before taking Secukinumab , what precautions must I follow?

​STOP taking Secukinumab and let your doctor know if you develop a rash or allergy. Rash due to allergic reaction to Secukinumab is rare. Possible symptoms of allergic reactions are:

  • rash, hives, or itching
  • red, swollen, blistered or peeling skin with or without fever
  • wheezing or tightness in the chest or throat
  • trouble breathing or talking
  • unusual hoarseness
  • swelling of the mouth, face, lips, tongue or throat

Tell your doctor immediately if you experience any symptoms of infection such as temperature exceeding 38°C, chills, cough, painful or bloody urination, feeling very tired or weak.

Let your doctor or dentist know that you are taking Secukinumab, as it may increase the risk of infection after a surgical procedure.

Secukinumab may cause new onset or worsening of inflammatory bowel disease. Consult your doctor immediately if you develop new symptoms of persistent or severe stomach pain or diarrhoea.

While having treatment with Secukinumab, you must see your doctor as scheduled to monitor response to treatment and minimize any possible side effect.

Avoid pregnancy while you are taking Secukinumab as the effect in pregnant woman is unknown. You must use effective contraception while using Secukinumab and for at least 20 weeks after the last dose.

If you are breastfeeding or planning to breastfeed, discuss with your doctor to decide if you should breastfeed or use Secukinumab. After using Secukinumab, you should not breastfeed for at least 20 weeks after the last dose.

Immunization status should be current before starting the medicine. Do not receive any live vaccine while you are on Secukinumab. Always consult your doctor before going for immunisation.

Secukinumab may interact with other medicine or supplement that you are taking. Inform the doctor, pharmacist or specialty nurse (such as dermatology, gastroenterology or rheumatology) before starting on a new medicine or supplement.

What food or medicine must I avoid when I take Secukinumab ?

Secukinumab - Additional Information

  • Updated on 10/24/2017 12:00:00 AM
  • Article contributed by Pharmacy, Rheumatology & Immunology Singapore General Hospital
The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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