Tibolone may cause some unwanted side effects. Generally, the common side effects tend to occur at the beginning of the treatment. Such side effects include:
Inform the doctor if any of the aboce side effects lasts for more than a few months after the beginning of the treatment or if they become serious or bothersome.
Rare but serious effects may occur. Contact the doctor as soon as possible if any of the following are noticed:
of the women will not experience menstruation during treatment. However, you may experience
irregular bleeding or spotting during the first 3 months of starting tibolone. If
this continue for longer than 6 months, please see your doctor as soon as
If you are due to have an operation, tell the surgeon you are taking tibolone. You may need to stop taking tibolone a few weeks before the operation to reduce the risk of a blood clot.
Some medicines may interfere with the effects of tibolone and cause irregular bleeding such as blood thinning medicines (e.g. warfarin). Please inform your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including herbal medicines or natural products.
Studies have shown that tibolone may be associated with a slight increased risk of both stroke and endometrial cancer. It may also be associated with an increased risk of breast cancer. Regularly check your breast for any changes such as dimpling of the skin, changes in the nipple, or any lumps you can see or feel. The risk of breast cancer returns to normal within a few years after stopping treatment.
If you have any concerns, please discuss with your doctor. Your doctor will consider the benefits versus its risks when they prescribed the treatment to ensure it remains suitable for you.
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