Lapatinib
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Lapatinib

Drug Class: Commonly Known As: Category:
Dual Kinase Inhibitor Tykerb® Cancer-related

Lapatinib - What is it for

​Lapatinib is an oral targeted medication used to treat advanced breast cancer. It is normally given together with another oral medication, either Capecitabine or Letrozole.

Lapatinib - Side Effects, Precautions, and Contraindications

What side effects can Lapatinib cause?

  • Nausea and vomiting
  • Diarrhea
  • Palms of the hands or soles of the feet may become numb, sore, red or dry
    Especially if Lapatinib is taken together with Capecitabine.
  • Rash, dry skin, itch
  • Tiredness and lack of energy

Inform your doctor if any of the following occurs:

  • Fever of 38°C or higher
  • Sores or ulcers in mouth and throat
  • Unusual bleeding, bruising or black tarry stools
  • Rapid or irregular heartbeat
  • Chest pain, cough or shortness of breath
  • Unusual water retention or swelling of the hands or feet
  • Yellowing of the skin or eyes or dark tea-coloured urine
  • Side effects become severe

Before taking Lapatinib , what precautions must I follow?

  • Use effective birth control during treatment with Lapatinib. Inform your doctor if you suspect pregnancy.
  • Inform your doctor or pharmacist if you are taking any other medication or supplements.

What food or medicine must I avoid when I take Lapatinib ?

Avoid taking grapefruit or its juice while you are on Lapatinib.​

Lapatinib - Dosage and How to Use

How should Lapatinib be used?

It is a tablet taken by mouth, usually once daily at around the same time each day. Take the exact number of tablets instructed by your doctor.
Take on an empty stomach i.e. at least 1 hour before or 1 hour after food.

What should I do if I miss a dose?

If you miss a dose of Lapatinib, take the next scheduled dose at your usual dosing time. Do not make up for the missed dose or double dose the next day.

What should I do if I overdose?

If you overdose on this medication, inform your doctor immediately.

Lapatinib - Handling

How should I handle Lapatinib safely?

Do not crush or break the tablets.

Lapatinib - Storage

How should I store Lapatinib ?

;#Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#Store at room temperature;#

How should I dispose of Lapatinib safely?

Lapatinib - Additional Information

  • Updated on 2/28/2019 12:00:00 AM
  • Article contributed by Department of Pharmacy National Cancer Centre Singapore
The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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