Riociguat is used to treat Pulmonary Arterial
Hypertension and patients with a specific type of
Pulmonary Hypertension called Chronic
Thromboembolic Pulmonary Hypertension (CTEPH).
In CTEPH, the blood vessels of the lungs are blocked or
narrowed with blood clots. This results in
breathlessness and high blood pressure in the lungs.
Riociguat can help patients with CTEPH who cannot
undergo surgery to relieve the blockage, or in patients
whom increased blood pressure in the lungs remains
or returns after surgery.
Every individual will respond to treatment in different
ways. It is important you have realistic expectations of
what the treatment can do.
Riociguat is a type of medication called a guanylate
cyclase (sGC)-stimulator. It works by widening the
pulmonary arteries (the blood vessels that transfer
oxygen from the lungs to the blood), making it easier
for the heart to pump blood through the lungs.
As this medication may cause birth defects, female
patients of childbearing age should take precautions
by using at least 2 reliable methods of contraception to
avoid pregnancy. If you suspect you may be pregnant,
inform your Cardiologist as soon as possible.
Riociguat is available as 1mg and 2.5mg tablets, to be taken by mouth three times a day. Riociguat is initially started at a lower dose. Your condition will be monitored closely. Your Cardiologist may later adjust your dosage to better control your condition.
You may take Riociguat with or without food.
If you forget to take a dose, take it as soon as you
remember but do not take two doses at once.
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